Jacopo Torriti, The Annunciation
13th century
Mosaic
Apse, Basilica of Santa Maria Maggiore, Rome
God's mouth emits the spiritus sanctus, punningly the Holy Spirit and "holy breath." Strikingly, God is pictured not as a hand or an old man but as the Son. Below, Gabriel greets Mary with the blessing gesture and she responds with a gesture that one historian says means reserve and detachment. (See Luke 1:26-38.)
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Photographed at the basilica by Richard Stracke, shared under Attribution-NonCommercial-ShareAlike license.