Church of San Nicolás, Portomarín, Spain
The palms-out gesture is common in Annunciations of this period. Hanging on the plant between the two figures are two bunches of grapes, possibly symbolic of the blood that Christ will shed in the Crucifixion and the wine that commemorates that sacrifice.
Read more about the Annunciation.
Photographed at the church by Richard Stracke, shared under Attribution-NonCommercial-ShareAlike license.